Codeine is absorbed from the gastrointestinal tract with greatest plasma focus occurring 60 minutes post administration. The presence of a substantial-Extra fat, higher-calorie meal didn't drastically impression the PK of codeine.Promethazine with Codeine Oral Alternative just isn't advisable for use in Expecting Women of all ages [see Use in Speci… Read More

For pregnant mice and rats that received promethazine at doses 0.fifteen to three occasions the MRHD, throughout different periods of gestation, there were results of amplified fetal resorptions and skeletal fragility, decreased pup pounds, and developmental delays of pups ( see Info). In experiments with normotensive pregnant rabbits, which gained… Read More